When answering this question, focus on a specific project where you faced significant challenges. Start by briefly describing the project and its objectives. Then, detail the obstacles you encountered, such as issues with stability, solubility, or bioavailability. Explain the steps you took to overcome these challenges, highlighting your problem-solving skills, technical knowledge, and any innovative approaches you used. Conclude with the successful outcome of the project and any lessons learned. For example:
"In one of my previous roles, I worked on developing a new oral formulation for a poorly soluble drug. The main challenge was to enhance the drug's solubility without compromising its stability. I conducted extensive research on various solubilization techniques and decided to use a solid dispersion method. After optimizing the formulation parameters through a series of experiments, we achieved a stable and highly soluble formulation. This project not only improved my technical skills but also taught me the importance of persistence and creative problem-solving."
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